This technical guidance factsheet was developed as part of a series of practical on-farm hatchery management guides based on the FAO Artemia Manual. It provides a concise, user-friendly reference for hatchery operators on the harvesting of Artemia nauplii and their effective separation from unhatched cysts and empty shells. The factsheet describes key procedures for harvest preparation, nauplii collection using concentrator-rinser or sieve-based methods, and subsequent handling options, including direct feeding, short-term storage or enrichment. It also highlights critical operational considerations to maximize nauplii quality and purity while minimizing the risk of larval mortality associated with the presence of cyst shells. Presented in a highly visual format, the guide transforms the detailed information contained in the FAO Artemia Manual into a practical tool that supports the safe and effective production of high-quality Artemia for aquaculture hatcheries.